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1 In June 2025, the MHRA reinforced this in a public safety update, advising that GLP-1 medicines (a class of weight management and diabetes medications that includes Wegovy, Mounjaro, and Ozempic) must not be taken during pregnancy, while trying to get pregnant, or during breastfeeding
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[1] The medication carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Inadequately treated hypothyroidism significantly impairs metabolism, making weight loss extremely difficult and worsening insulin sensitivity
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